Endocrine Abstracts

Introduction: Pituitary ACTH-dependent Cushing’s syndrome (CS) is a condition characterized by an overproduction of cortisol due to pituitary adenoma which infers high morbidity and mortality. Transsphenoidal surgery (TSS) is the first-line therapy of an ACTH-secreting pituitary adenoma. But, even after surgical resection of the adenoma, up to 50% of cases may develop a recurrence of the disease.Case presentation: A woman, 32 year-old, developed rec...

Introduction: Ectopic Cushing’s syndrome (ECS) is a rare disease caused by ACTH secretion by extrapituitary neuroendocrine tumors, characterized by high mortality. Despite the clinical sings of Cushing’s syndrome, difficult access to reliable clinical examinations, leads to a delay in diagnosis and the choice of optimal treatment tactics. Small-cell lung cancer patients with ECS have a very poor prognosis. Case report: A 35-year-old woman ...